Piccolo
has been specifically developed with three
top pharma companies to optimise conditions
for protein expression in bacterial and
insect baculovirus expression systems. Piccolo
is designed to support to vary multiple
expression parameters rapidly in parallel
to enable protein expression to be achieved
in days rather than months, These systems
are a key tool in the expression tool box
to enhance availability of protein early
in the discovery cycle to enable determination
of structures and improve effectiveness
of lead optimisation
GSK
chose Piccolo to support their high
throughput parallel expression activities
Sonata,
TAP’s latest development, can be
optimised to expand mammalian and insect
cells growing in suspension. The system
can also be used to culture insect cells
for bacculovirus expression and creation
of baculovirus stocks for infection.
