ambr™
mimics the characteristics of classical
bioreactors at microscale (10-15ml), by
using cost effective, disposable micro-bioreactors,
controlled by an automated workstation.
ambr
enables the rapid evaluation of multiple
bioreactor cultures at microscale, increasing
productivity in cell line development with
significant savings on materials and labour.
Central
to the system is the new
ambr micro bioreactor
– specifically designed
to mimic the characteristics
of a larger scale bioreactor.
To learn
more about the unique
design and key features
of the ambr micro
bioreactor - take an interactive
tour.
Following extensive
R&D in collaboration with leading bioprocessing
groups, the first automated ambr
workstations are now available
– offering parallel processing and
evaluation of up to 24 micro bioreactor
experiments in an automated bench top system.
Closed loop control of pH and DO
with independent control of O2
and CO2 for each vessel
Automated liquid handling for reactor
set-up, feeds, base addition and sampling
Easy installation into laminar flow
hood allowing aseptic operation
Optional integrated viable cell counting
A better tool for cell line selection
and development - closely mimics the
conditions of larger scale bioreactors
Simplified adoption of Quality by
Design (QbD) principles for cell culture
development
Significant reduction in cost per
experiment
More experiments with less operator
time for set up and clean down
Cell line selection
Cell line stability
Media feed strategies
Process robustness experimentation
in support of ‘quailty by design‘
studies
Automation of DOE approaches to process
optimisation
ambr offers
an accurate and cost-effective approach
to replicating bioreactor conditions, and
can be used as a microscale model for a
wide range of upstream processes such as
cell line selection and process optimisation.
