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Piccolo
 
Piccolo - System Overview - A new fully automated system for the rapid optimisation of recombinant protein production in microbial or insect cells
Rapid optimisation of protein production - Piccolo
Piccolo™ is a new, fully automated system for the rapid optimisation of recombinant protein production in microbial or insect cells.
  The system has been designed in conjunction with a consortium of 3 leading global pharmaceutical companies and offers the flexibility to vary and control a wide range of protein culture parameters independently and conduct experiments in parallel.
 
Piccolo automates
 
  • Culture inoculation/infection
  • Lysis
  • Growth/induction
  • Affinity purification
Piccolo offers
 
  • Significant reduction in protein production timelines (from months to days)
  • Improved run-to-run consistency and site-to-site process transfer
  • Provision of improved data for experimental strategy design
  • Focus on maintaining protein quality
  Piccolo enables consistent and reliable determination of the best construct, host strain, culture conditions and induction/infection dynamics for individual target proteins.
Applications include
 
  • Structural biology
  • Assay development
  • Protein engineering
  Piccolo is currently being used at 3 leading pharmaceutical companies including Merck and GSK
  For more information on Piccolo:
  Get more detail on the systems' Key Applications
  Discuss your requirements with Ian Ransome, Sales Director
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