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Cello System Overview. Cello is a new automated system for mammalian cell culture in plates
High throughput clone maintenance and selection - Cello
Cello™ is a new automated system for mammalian cell culture in plates, and enables efficient selection of optimal clones.
  Cello cultures multiple clones in parallel, from seeding through expansion and sub-cloning. The system provides the throughput and capacity needed to support several projects running in parallel, with minimal operator involvement.
  Cello cultures both adherent and non-adherent cell lines, growing in 384, 96, 24 and 6-well plates.
 
Cello automates
 
  • Cell seeding of transfected cells from bulk supply
  • Media change and re-feed
  • Expansion of cells into fresh wells
  • Enzymatic detachment of adherent cell lines
  • "Cherry picking" cells from individual wells for expansion
  • Harvest of cells or supernatant for output for cell banking or screening
  • Measurement of cell growth
  Cello also manages the complex scheduling and logistics inherent in culturing multiple clones simultaneously. It improves productivity wherever cells are grown in plates, particularly for the generation, maintenance and expansion of stable cell lines.
 
  • Significant increase in throughput and quality of clone production
  • Selection of the best cell lines from many clones
  • Larger cloning experiments, expression systems and experimental conditions
  • Biological diversity in transfected cell populations
  • Reduced timelines for cell line development
Applications include
  Stable cell line generation for
 
  • Drug discovery
  • Therapeutic proteins
  • Stem cells
  Cell culture and assay assembly for
 
  • ADME testing and transport
  • Permeability testing
  Cello is currently is being used at 5 leading pharmaceutical/biotechnology companies including AstraZeneca, Genmab and Novo supporting their cell line development activities.
  For more information on Cello:
  Get more detail on the systems' Key Applications
  Discuss your requirements with Ian Ransome, Sales Director
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