Cell
line production and high throughput clone selection
- Cello |
| |
Cello™
is a new automated cell line production system for
mammalian cell culture in plates, and enables efficient
selection of optimal clones and cell lines. |
| |
Cello cultures
multiple cell lines in parallel, from seeding through
expansion and sub-cloning. The cell line production
system provides the throughput and capacity needed
to support several projects running in parallel,
with minimal operator involvement. |
Cello cultures
both adherent and non-adherent cell lines, growing
in 384, 96, 24 and 6-well plates. |
| Cello
automates: |
| |
- Cell line production and high throughput clone
selection
- Cell seeding of transfected cells from bulk
supply
- Media change and re-feed
- Expansion of cells into fresh wells
- Enzymatic detachment of adherent cell lines
- "Cherry picking" cells from individual
wells for expansion
- Harvest of cells or supernatant for output
for cell banking or screening
- Measurement of cell growth
|
| |
Cello also
manages the complex scheduling and logistics inherent
in culturing multiple cell lines simultaneously.
It improves cell line production and productivity
wherever cells are grown in plates, particularly
for the generation, maintenance and expansion of
stable cell lines. |
| Cello
offers: |
| |
- Significant increase in throughput and quality
of clone production
- Selection of the best cell lines from many
clones
- Larger cloning experiments, expression systems
and
experimental conditions
- Biological diversity in transfected cell populations
- Reduced timelines for cell line development
|
 |
| |
Stable
cell line generation for |
| |
- Drug discovery
- Therapeutic proteins
- Stem cells
|
| |
Cell
culture and assay assembly for |
| |
- ADME testing and transport
- Permeability testing
|
| |
Cello
is currently being implemented at 3 leading pharmaceutical/biotechnology
companies. |
| |
|
