Automation
for protein production - Piccolo |
| |
Piccolo™
is a new, automation for protein production system
for the rapid optimisation of recombinant protein
in microbial or insect cells. |
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The system has been
designed in conjunction with a consortium of 3 leading
global pharmaceutical companies and offers the flexibility
to vary and control a wide range of automation for
protein production and culture parameters independently
and conduct experiments in parallel. |
| Piccolo
automates: |
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- Automation for protein production
- Culture inoculation/infection
- Growth/induction
- Harvest
|
- Lysis
- Affinity purification
|
|
| Piccolo
offers: |
| |
- Significant reduction in automation for protein
production timelines
(from months to days)
- Improved run-to-run consistency and site-to-site
process transfer
- Provision of improved data for experimental
strategy design
- Focus on maintaining protein quality
|
| |
Piccolo
enables consistent and reliable determination of
the best construct, host strain, culture conditions
and induction/infection dynamics for individual
target proteins. |
| Applications
include: |
| |
- Structural biology
- Assay development
- Protein engineering
|
| |
Piccolo
is currently being implemented by 3 leading global
pharmaceutical companies. |
| |
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