Automated
clone selection - Cello |
| |
Cello™
is a new automated system for automated clone
selection enabling efficient selection of optimal
clones to provide cell lines for biologics production
and cell based research. |
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Cello cultures multiple clones
in parallel, from seeding through expansion and
sub-cloning. The system provides the throughput
and capacity needed to support several projects
running in parallel, with minimal operator involvement. |
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Cello cultures both adherent and
non-adherent cell lines, growing in 384, 96, 24
and 6-well plates. |
| Cello
automates: |
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- Automated clone selection
- Cell seeding of transfected cells from bulk
supply
- Media change and re-feed
- Expansion of cells into fresh wells
- Enzymatic detachment of adherent cell lines
- "Cherry picking" cells from individual
wells for expansion
- Harvest of cells or supernatant for output
for cell banking or screening
- Measurement of cell growth
|
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Cello
also manages the complex scheduling and logistics
inherent in culturing multiple clones simultaneously.
It improves productivity wherever cells are grown
in plates, particularly for the generation, maintenance
and expansion of stable cell lines. |
| Cello
offers: |
| |
- Significant increase in throughput and quality
of automated clone selection and production
- Selection of the best cell lines from many
clones
- Larger cloning experiments, expression systems
and experimental conditions
- Biological diversity in transfected cell
populations
- Reduced timelines for cell line development
|
| Applications
include: |
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Stable
cell line generation for |
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- Drug discovery
- Therapeutic proteins
- Stem cells
|
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Cell
culture and assay assembly for |
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- ADME testing and transport
- Permeability testing
|
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Cello
is currently is being used at 5 leading pharmaceutical/biotechnology
companies including AstraZeneca,
Genmab and Novo
supporting their cell line development activities. |
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Get more detail
on key applications, including: automated
clone selection |
| |
Learn more about
the
full range of TAP Cell Culture Systems |
| |
Discuss your
requirements with Ian
Ransome, Sales Director |
